Researchers believe they may have found the cause of Crohn’s disease

Crohn's disease is a chronic inflammatory condition that affects the bowel.

Up to now, there was very little known about what might cause Crohn's to develop but new research has established a key factor: fungus. According to Global News, researchers have identified a type of fungus and two types of bacteria that they believe contribute to the reason why some people get Crohn's. Senior author of the study, Mahmoud A. Ghannoum, PhD, a professor and director of the Center for Medical Mycology at Case Western Reserve and University Hospitals Cleveland Medical Center, has spoken about the research:

“We already know that bacteria, in addition to genetic and dietary factors, play a major role in causing Crohn’s disease. Essentially, patients with Crohn’s have abnormal immune responses to these bacteria, which inhabit the intestines of all people".

Although it was previously noted that E.coli bacteria may increase the risk of Crohn's, this new study has shown that a bacteria named erratia marcescen and a fungus, Candida tropicalis, are also linked to the condition. It is thought that when the aforementioned bacteria and fungus come together, a 'biofilm' is formed and this can bring on inflammation of the intestines and bowel, thus proving a trigger for Crohn's. Ghannoum further elaborated on the research, advising that is a major step in figuring out what causes Crohn's and helping to develop more effective treatment options.

“Our study adds significant new information to understanding why some people develop Crohn’s disease. “Equally important, it can result in a new generation of treatments, including medications and probiotics, which hold the potential for making qualitative and quantitative differences in the lives of people suffering from Crohn’s".

For more information on Crohn's Disease contact the Irish Society for Colitis and Crohn's Disease on 01) 872 1416 or visit the website here.