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18th November 2024
10:36am GMT
Although initially marketed as a medication for type 2 diabetes, Ozempic has gained widespread attention for its weight-loss effects in recent years.
On the Show Me the Science podcast, Professor Luke O'Neill explored the broader impacts of the drug that have since been discovered and are lesser-known.
According to Prof. O'Neill, Ozempic could reduce the risk of heart attack and stroke by as much as 20%.
"That would have a big effect because heart attacks and strokes are very serious," he said.
"There's going to be a saving there, first of all, because of the drop in heart attacks."
The drug’s primary use is to increase levels of a hormone called GLP-1, which controls appetite.
Interestingly, the origins of GLP-1 research trace back to the gila monster, a species of giant lizard, O’Neill says.
"Gila monsters eat a meal and don’t need to eat for months," Prof. O’Neill explained.
"Their body makes this GLP-1 substance, which regulates how they burn glucose and prevents obesity."
This appetite regulation means that Ozempic has the potential to address the global obesity crisis.
Prof. O’Neill also explained the other potential benefits, including positive effects on conditions like sleep apnea, arthritis, Parkinson’s disease, and infertility.
Despite its promising benefits, Prof. O’Neill urged people to be cautious around prolonged use of Ozempic.
The drug’s side effects can include nausea, gastrointestinal issues, and a more serious concern; muscle wasting.
"You lose some muscle mass, as well as fat tissue," he said.
"This can be quite serious, especially in older people, because weaker muscles increase the risk of falls and hinder day-to-day activities."
O’Neill acknowledged the need for more research and careful usage, but said Ozempic's has potential to bring positive change, particularly in tackling obesity and its related health challenges.
