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Published 11:36 31 Aug 2019 BST
Updated 11:41 31 Aug 2019 BST
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Unfortunately, the mother of the pups has not been located.
ISPCA Centre Manager, Hugh O’Toole, said: "Leaving such young puppies without their mother most definitely put their lives at risk and it is impossible to understand how someone could just leave six defenceless puppies, on the side of a road, left for dead. It’s simply inhumane.
"We exhausted our efforts to locate the mother dog as we are worried she could be suffering from mastitis and may need veterinary attention. She is likely looking for her puppies and we are appealing to the public to get in touch if they have any information."
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