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Published 13:10 12 Apr 2018 BST
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Also on the show this week is style guru and one half of one of the most popular TV duos of the 00s, Trinny Woodall. Trinny and Susannah rose to fame in 2001 when their show What Not to Wear became the style bible for women across the UK and Ireland.
Trinny will be discussing her career path in the fashion industry but will also be sharing her story of trying to have a baby after going through nine rounds of IVF and suffering two miscarriages before finally becoming pregnant with her daughter.
Laura Brennan, a 25-year-old Clare woman who has been diagnosed with terminal cervical cancer, will also be sharing her story and telling viewers why she strongly believes that young girls should be vaccinated against the HPV virus, one of the chief causes of cervical cancer.
And we’ll hear about the unlikely friendship struck up between retired District Court judge Gillian Hussey and reformed former criminal Paul Mahon after they met through rehabilitation organisation Tiglin.
Providing the music for the night will be Irish band, Kodaline, who will be performing their latest single and having a quick catch up with Ryan.
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