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Published 13:33 20 Apr 2022 BST
Updated 15:45 22 Apr 2022 BST
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"Rio died of uveal melanoma, a very aggressive and rare form of cancer," they said. "We would beg everyone reading this to get their eyes tested at least once a year, which might save their loved ones from this cancer."
Other Hollywood stars have paid tribute to Rio, since his brother announced his passing earlier this week.
Queens of the Stone Age's Josh Homme said: "Rio just knew things. Esoteric things. Off-the-map things. Secret things. Wonderful things.
"He knew these things because of his charm, wit, honesty, character and tough personality. He was a real man in a sea of poseurs."
Vince Vaughn, who starred alongside Rio in a number of films including Swingers and Fred Clause, described Rio as "loyal and funny as anyone could be".
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